کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3310954 1210751 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Percutaneous radiofrequency ablation with internally cooled wet electrodes versus cluster electrodes for the treatment of single medium-sized hepatocellular carcinoma
ترجمه فارسی عنوان
با استفاده از الکترودهای خنک کننده داخلی در مقابل الکترودهای خوشه ای برای درمان کارسینوم سلول های تک سلولی متوسط
کلمات کلیدی
الکترود خوشه، کارسینوم سلول های خونی الکترود مرطوب خنک داخلی، فرسایش بسامد رادیویی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
چکیده انگلیسی

BackgroundTo compare the effectiveness and complications of radiofrequency ablation (RFA) using cluster electrodes or internally cooled wet (ICW) electrodes in patients with medium-sized hepatocellular carcinomas (HCCs).MethodsBetween February 2008 and September 2013, 40 patients (31 men and 9 women; mean age, 61.2 years) with a single medium-sized HCC (mean size, 3.5 ± 0.5 cm; range, 3.1–5.0 cm) underwent percutaneous RFA with cluster electrodes (n = 19) or ICW electrodes (n = 21). Technical success, technical effectiveness, ablation volume, major complications, and local tumor progression were compared.ResultsAfter the initial RFA, technical success was achieved in 84% of patients and 90% of patients treated by cluster electrodes and ICW electrodes, respectively (P = 0.654). At 1 month, technical effectiveness was achieved by cluster electrodes and ICW electrodes in 84% and 100% of patients, respectively (P = 0.098). During follow-up period (mean, 17.8 months; range, 0–67 months), the median local tumor progression rates were 21.3 months in the cluster group and 31.0 months in the ICW group. The 6-month, 1-, 2-, and 4-year local tumor progression rates were significantly lower after RFA with ICW electrodes (0%, 7%, 25%, and 57%, respectively) than after RFA with cluster electrodes (26%, 33%, 53%, and 68%, respectively; P = 0.036). Major complications occurred in 15.8% of patients treated with cluster electrodes and in 4.8% of patients treated with ICW electrodes (P = 0.331).ConclusionFor the treatment of medium-sized HCCs, percutaneous RFA using ICW electrodes results in lower rate of local tumor progression and fewer serious complications, compared to cluster electrodes.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gastrointestinal Intervention - Volume 3, Issue 2, December 2014, Pages 98–103
نویسندگان
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