Impact sur les fonctions cognitives des anticholinergiques prescrits chez les patients âgés de plus de 65 ans pour hyperactivité vésicale

Urinary incontinence due to an overactive bladder has both physical and psychological consequences. Anticholinergic drugs are chosen for first-line treatment, with proven effectiveness on urinary symptoms. However, this class of drug has deleterious effects on cognitive functions such as memory, learning, reasoning and sleep via action on muscarinic receptors located in the central nervous system. In the elderly, cognitive disorders are often associated with urinary incontinence.