کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3329192 1212379 2011 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Circulating microRNAs: Association with disease and potential use as biomarkers
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی هماتولوژی
پیش نمایش صفحه اول مقاله
Circulating microRNAs: Association with disease and potential use as biomarkers
چکیده انگلیسی

The control of gene expression by microRNAs influences many cellular processes and has been implicated in the control of many (patho)physiological states. Recently, microRNAs have been detected in serum and plasma, and circulating microRNA profiles have now been associated with a range of different tumour types, diseases such as stroke and heart disease, as well as altered physiological states such as pregnancy. Here we review the disease-specific profiles of circulating microRNAs, and the methodologies used for their detection and quantification. We also discuss possible functions of circulating microRNAs and their potential as non-invasive biomarkers.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Critical Reviews in Oncology/Hematology - Volume 80, Issue 2, November 2011, Pages 193–208
نویسندگان
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