Construction, expression, and characterization of an anti-tumor immunotoxin containing the human anti-c-Met single-chain antibody and PE38KDEL

► A recombinant immunotoxin, anti-c-Met/PE38KDEL, was constructed. ► This immunotoxin can inhibit the proliferation of human hepatoma cell line. ► This immunotoxin can inhibit the growth of hepatocellular carcinoma xenograft.