کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3355736 | 1217208 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Basophils and mast cells: Underdog in immune regulation?
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
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چکیده انگلیسی
Mast cells and basophilic granulocytes have recently been recognized as potent immunomodulatory cells. Whereas these cells originally were described as potent cells that release their pro-inflammatory contents (i.e. histamine) unconstrained after activation, nowadays this process is considered to be much more subtle. Especially, via the release of pro- and anti-inflammatory cytokines basophils and mast cells now can steer an immune response. Recently, it has become evident that at least in murine models basophils are crucial for the initial induction of a Th2 response in immunologically naive mouse.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunology Letters - Volume 138, Issue 1, July 2011, Pages 28–31
Journal: Immunology Letters - Volume 138, Issue 1, July 2011, Pages 28–31
نویسندگان
Edward F. Knol, Maciej Olszewski,