کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3368321 | 1592313 | 2009 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
ANCA-associated vasculitides: Pathogenetic aspects and current evidence-based therapy
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: ANCA-associated vasculitides: Pathogenetic aspects and current evidence-based therapy ANCA-associated vasculitides: Pathogenetic aspects and current evidence-based therapy](/preview/png/3368321.png)
چکیده انگلیسی
A lot of progress has been made regarding the therapy of ANCA-associated vasculitides in the past decades. Cyclophosphamide still is standard therapy for remission induction in generalized disease, however, duration and cumulative dose of cyclophosphamide have been curtailed successfully to reduce toxicity. MTX is a safe alternative for remission induction in early systemic disease and medications available for remission maintenance have been extended. Rituximab and TNFalpha-antagonists represent promising options for refractory disease. The current evidence of therapy of ANCA-associated vasculitides is summarized in this review.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Autoimmunity - Volume 32, Issues 3–4, May–June 2009, Pages 163–171
Journal: Journal of Autoimmunity - Volume 32, Issues 3–4, May–June 2009, Pages 163–171
نویسندگان
J.U. Holle, W.L. Gross,