کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3416105 | 1224993 | 2007 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The naturally acquired immunity in severe malaria and its implication for a PfEMP-1 based vaccine
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The naturally acquired immunity in severe malaria and its implication for a PfEMP-1 based vaccine The naturally acquired immunity in severe malaria and its implication for a PfEMP-1 based vaccine](/preview/png/3416105.png)
چکیده انگلیسی
Malaria vaccine development has so far been largely focused on antigens involved in parasite invasion pathways rather than on antigens associated with severe disease and naturally acquired immunity. Individuals repeatedly exposed to Plasmodium falciparum will eventually become immune to severe disease. Parasite-derived antigens expressed on the infected red blood cell (iRBC) surface are the main targets of protective immunity and can be explored as a rational alternative in development of an anti-malaria vaccine.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microbes and Infection - Volume 9, Issue 6, May 2007, Pages 777–783
Journal: Microbes and Infection - Volume 9, Issue 6, May 2007, Pages 777–783
نویسندگان
Qijun Chen,