کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3423391 | 1227025 | 2012 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: The evolution of Trypanosoma cruzi: the ‘bat seeding’ hypothesis The evolution of Trypanosoma cruzi: the ‘bat seeding’ hypothesis](/preview/png/3423391.png)
Recent discussions on the evolution of Trypanosoma cruzi have been dominated by the southern super-continent hypothesis, whereby T. cruzi and related parasites evolved in isolation in the mammals of South America, Antarctica and Australia. Here, we consider recent molecular evidence suggesting that T. cruzi evolved from within a broader clade of bat trypanosomes, and that bat trypanosomes have successfully made the switch into other mammalian hosts in both the New and Old Worlds. Accordingly, we propose an alternative hypothesis – the bat seeding hypothesis – whereby lineages of bat trypanosomes have switched into terrestrial mammals, thereby seeding the terrestrial lineages within the clade. One key implication of this finding is that T. cruzi may have evolved considerably more recently than previously envisaged.
Journal: - Volume 28, Issue 4, April 2012, Pages 136–141