کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3840688 | 1247930 | 2012 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Relationship between adipokines and coronary artery aneurysm in children with Kawasaki disease
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کلمات کلیدی
LMWTNFCALsIVIgHMWALTRBCHCTESRMMPWBCMCPBSA - BSAAST - آسپارتات ترانس آمینازAspartate aminotransferase - آسپارتات ترانس آمیناز یا AST Alanine aminotransferase - آلانین آمینوترانسفرازinterleukin - اینترلوکینIntravenous immunoglobulin - اﯾﻤﻮﻧﻮﮔﻠﻮﺑﻮﻟﯿﻦ ورﯾﺪیKawasaki disease - بیماری کاوازاکیerythrocyte sedimentation rate - سرعت رسوب گلبول قرمزbody surface area - سطح بدنCoronary artery lesions - ضایعات عروق کرونرtumor necrosis factor - فاکتور نکروز تومورmatrix metalloproteinase - ماتریکس متالوپروتئینازhematocrit - هماتوکریتHemoglobin - هموگلوبینhigh molecular weight - وزن مولکولی بالاlow molecular weight - وزن مولکولی کمmonocyte chemoattractant protein - پروتئین شیمیایی monocyte chemoattractantC reactive protein - پروتئین واکنشی CCRP - پروتئین واکنشی سی یا سی. آر. پی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Relationship between adipokines and coronary artery aneurysm in children with Kawasaki disease Relationship between adipokines and coronary artery aneurysm in children with Kawasaki disease](/preview/png/3840688.png)
چکیده انگلیسی
Body fat is an important source of adipokines not only in association with energy balance, but also with inflammatory and immune responses. This study investigated the relationship between serum levels of adipokines and coronary artery aneurysm in patients with Kawasaki disease (KD). Levels of leptin, adiponectin, and resistin were measured in 165 cases, including 4 groups: the control group (n = 85), KD with normal coronary arteries (n = 41), KD with dilatation and/or ectasia (n = 31), and KD with coronary aneurysm (n = 8). White blood cells counts (WBC), red blood cells counts (RBC), hemoglobin (HB), Hematocrit (Hct), platelet count, C reactive protein (CRP), and erythrocyte sedimentation rate (ESR) were tested in children. Levels of adiponectin and resistin levels were significantly elevated; hemoglobin significantly decreased in the group of KD with coronary aneurysm compared with the controls or other KD subgroups. There were markedly positive relationships between levels of resistin and CRP, and negative relationships between levels of resistin and RBC in patients with KD. Levels of adiponectin, resistin, and hemoglobin were associated with the development of coronary aneurysm in children with KD. The up-regulation of resistin secreted from adipose tissue may be closely linked to up-regulation of systemic proinflammatory markers in acute KD.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Translational Research - Volume 160, Issue 2, August 2012, Pages 131-136
Journal: Translational Research - Volume 160, Issue 2, August 2012, Pages 131-136
نویسندگان
Ruixi Liu, Bo He, Fang Gao, Qian Liu, Qijian Yi,