کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3979384 | 1257331 | 2010 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Carcinomes canalaires in situ (CCIS). Caractéristiques histopathologiques et traitement : analyse de 1 289 cas
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کلمات کلیدی
Tamoxifene - تاموسیفنtamoxifen - تاموکسیفنConservateur - حزب محافظه کارTraitement - درمانRadiotherapy - رادیوتراپیCancer du sein - سرطان پستانSurgery - عمل جراحیMastectomie - ماستکتومیMastectomy - ماستکتومی، پستانبرداریRadiothérapie - پرتو درمانیDuctal carcinoma in situ - کارسینوم داکتال در محلbreast carcinoma - کارسینوم سینه، کارسینوم پستان
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
تومور شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
From March 2003 to April 2004, were prospectively collected in France 1,289 ductal carcinoma in situ (DCIS) with data on diagnosis, patient and tumour characteristics, and treatments. Median age was 56 years (range, 30-84). DCIS was diagnosed by mammography in 87.6% of patients. Mastectomy (M), conservative surgery alone (CS) and conservative surgery with radiotherapy (CS + RT) were performed in 30.5, 7.8 and 61.7% of patients, respectively. Sentinel node biopsy (SNB) and axillary dissection (AD) were performed in 21.3 and 10.4% of patients, respectively. Hormone therapy was administered to 13.4% of the patients. Nuclear grade was low in 21% of patients, intermediate in 38.5% and high in 40.5%. Excision was considered complete in 92% (CS) and 88.3% (CS + RT) of patients. Treatment modalities varied widely according to region: mastectomy rate, 20-37%; adjuvant RT, 84-96%; hormone treatment, 6-34%. Our survey on current DCIS management in France has highlighted correlations between pathological features (tumour size, margin, grade) and treatment options, with several similar variations to those observed in recent UK and US studies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bulletin du Cancer - Volume 97, Issue 3, March 2010, Pages 301-310
Journal: Bulletin du Cancer - Volume 97, Issue 3, March 2010, Pages 301-310
نویسندگان
B. Cutuli, C. Lemanski, A. Fourquet, B. de Lafontan, S. Giard, S. Lancrenon, A. Meunier, R. Pioud-Martigny, F. Campana, H. Marsiglia, E. Mery, F. Penault-Llorca, E. Fondrinier, C. Tunon de Lara,