کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3980551 1257438 2009 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adjuvant therapy for resected extrahepatic cholangiocarcinoma: A review of the literature and future directions
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Adjuvant therapy for resected extrahepatic cholangiocarcinoma: A review of the literature and future directions
چکیده انگلیسی

SummaryCholangiocarcinoma is a rare neoplasm originating from the intra- or extrahepatic bile duct epithelium. Incidence has been increasing worldwide in the last three decades. Complete surgical resection provides the only possibility of cure, but even with resection 5-yr survival can be as low as 11%. Adjuvant therapy has the potential to play a crucial role in prolonging survival and local control. Retrospective series have suggested benefit to adjuvant radiation, chemotherapy or concurrent chemo-radiation. The scarce prospective data has not shown a survival benefit to adjuvant therapy. In this article we review and summarize the published data regarding adjuvant therapy for resected extrahepatic cholangiocarcinoma. Prospective, multi-institutional randomized trials are needed to clarify the role of adjuvant therapy in this disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cancer Treatment Reviews - Volume 35, Issue 4, June 2009, Pages 322–327
نویسندگان
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