کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4181098 1276635 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A Twin Study of Attention-Deficit/Hyperactivity Disorder Dimensions Rated by the Strengths and Weaknesses of ADHD-Symptoms and Normal-Behavior (SWAN) Scale
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
A Twin Study of Attention-Deficit/Hyperactivity Disorder Dimensions Rated by the Strengths and Weaknesses of ADHD-Symptoms and Normal-Behavior (SWAN) Scale
چکیده انگلیسی

BackgroundWhen symptom rating scales are used in the general population, there is severe skewness, with many individuals having no symptoms. While this has major implications for genetic designs that require extremely discordant and concordant (EDAC) siblings, little is known of the genetics of scales which seek to differentiate within the “no ADHD symptom” group.MethodsParents of Australian twins completed two attention-deficit/hyperactivity disorder (ADHD) questionnaires, the Australian Twin Behaviour Rating Scale (ATBRS), based on conventional DSM-IV symptom scores, and the Strengths and Weaknesses of ADHD-Symptoms and Normal-Behavior (SWAN) scale, which includes above-average performance on attention and activity. The two scales were compared in two age groups of same-sex twins, 528 pairs aged 6 to 9 and 488 pairs aged 12 to 20.ResultsParents reported higher levels of activity and attention in their twins when reporting using the SWAN scale than when using the ATBRS, and while the monozygotic (MZ) correlations were similar on both scales, the dizygotic (DZ) correlations were consistently higher on the SWAN. On DSM-IV based scales, parents exaggerated differences within those sibling pairs in the “with few ADHD symptoms” category.ConclusionsThe SWAN may provide a more realistic description of the ADHD phenotype for the selection of twin and sibling pairs for genetic analysis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biological Psychiatry - Volume 61, Issue 5, 1 March 2007, Pages 700–705
نویسندگان
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