کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4184023 1277296 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Affective dimensions as a diagnostic tool for bipolar disorder in first psychotic episodes
ترجمه فارسی عنوان
ابعاد عاطفی به عنوان یک ابزار تشخیصی برای اختلال دو قطبی در قسمت اول روانپریشی
کلمات کلیدی
مؤثر، دو قطبی، بعد، ابعاد، اندازه، اولین روانپریشی، فعال سازی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
چکیده انگلیسی

ObjectiveTo examine the predictive diagnostic value of affective symptomatology in a first-episode psychosis (FEP) sample with 5 years’ follow-up.MethodAffective dimensions (depressive, manic, activation, dysphoric) were measured at baseline and 5 years in 112 FEP patients based on a factor structure analysis using the Young Mania Rating Scale and Hamilton Depression Rating Scale. Patients were classified as having a diagnosis of bipolar disorder at baseline (BDi), bipolar disorder at 5 years (BDf), or “other psychosis”. The ability of affective dimensions to discriminate between these diagnostic groups and to predict a bipolar disorder diagnosis was analysed.ResultsManic dimension score was higher in BDi vs. BDf, and both groups had higher manic and activation scores vs. “other psychosis”. Activation dimension predicted a bipolar diagnosis at 5 years (odds ratio = 1.383; 95% confidence interval, 1.205–1.587; P = 0.000), and showed high levels of sensitivity (86.2%), specificity (71.7%), positive (57.8%) and negative predictive value (90.5%). Absence of the manic dimension and presence of the depressive dimension were both significant predictors of an early misdiagnosis.ConclusionThe activation dimension is a diagnostic predictor for bipolar disorder in FEP. The manic dimension contributes to a bipolar diagnosis and its absence can lead to early misdiagnosis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Psychiatry - Volume 29, Issue 7, September 2014, Pages 424–430
نویسندگان
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