Diagnosis of neuroborreliosis - Improved knowledge base for qualified antibody analysis and cerebrospinal fluid data pattern related interpretations

Antigen coating and evaluation by corrected AI is crucial for sensitivity of antibody assays. Specificity depends on a complete CSF data pattern including IgM. The post lyme disease is discussed regarding deficits in analysis, wrong clinical diagnosis, or borrelia as an unspecific trigger of a chronic disease with a multitude of possible causes.