کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4188632 | 1278008 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Efectos adversos de antipsicóticos atÃpicos, diferencias según sexo
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
روانپزشکی و بهداشت روانی
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چکیده انگلیسی
The adverse effects of atypical antipsychotic drugs vary depending on the sex of the patients. Females have a lower mean body weight than males, thus, at pharmacokinetic level, they have a lower clearance of some antipsychotics such as, clozapine and olanzapine. Among the most common adverse effects is highlighted the increase in corrected QT interval. Metabolic risks are also greater in females, with these being more likely to increase the weight after prolonged treatments, particularly with clozapine and olanzapine. Prolactin is increased more in females than in males after antipsychotic treatment. This adverse effect is more common with amisulpride, risperidone and paliperidone. Among the extrapyramidal secondary effects, akathisia is also more common in females. Gender variability should be taken into account in the future when calculating the dose, as well as when evaluating the adverse effects after antipsychotic treatment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: PsiquiatrÃa Biológica - Volume 21, Issue 3, SeptemberâDecember 2014, Pages 95-101
Journal: PsiquiatrÃa Biológica - Volume 21, Issue 3, SeptemberâDecember 2014, Pages 95-101
نویسندگان
EstÃbaliz Sáez de Adana GarcÃa de Acilu, Ana Isabel Cano, Ane Eizaguirre GarcÃa, Saioa López Zurbano, Aitor Francos Ajona, Jon Gaviña Arenaza, Batirtxe Artaraz Ocerinjauregui, Ana MarÃa Gonzalez-Pinto Arrillaga,