Non-invasive Quantification of Triglyceride Content in Steatotic Rat Livers by 1H-MRS

Hepatic fat approximations of the type TG/water overestimate hepatic steatosis degree because hepatic fat accumulation concurs with hepatic water exudation. Consequently, MRS-based approximations should be of the type TG/(TG + water) and contain a maximum number of TG resonances in the denominator.