Computational Analysis of Thoracic Multidetector Row HRCT for Segmentation and Quantification of Small Airway Air Trapping and Emphysema in Obstructive Pulmonary Disease

Small-airway AT segmentation in conjunction with emphysema segmentation through computer-assisted methodologies may provide better correlations with key PFT parameters, suggesting that the quantification of emphysema-related and small airway-related components of AT from thoracic HRCT has great potential to elucidate phenotypic differences in patients with chronic obstructive pulmonary disease.