Diagnostic Performance of a Prototype Dual-Energy Chest Imaging System

DE imaging at dose equivalent to DR exhibited similar overall ROC performance to DR, although the radiologists noted qualitatively improved visualization (eg, improved characterization of lesion margins, visibility of calcifications and rib fractures). DE imaging demonstrated significant improvement in diagnostic performance for specific subgroups, including subcentimeter lung lesions and lesions in the right upper lobe, each of which is a potentially important factor in detecting early-stage malignancy.