کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4224785 1609736 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Microwave treatment of renal cell carcinoma adjacent to renal sinus
ترجمه فارسی عنوان
درمان مایکروویو کارسینوم سلولی کلیه در مجاورت سینوسی کلیه
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
چکیده انگلیسی


• This study shows US-guided microwave ablation appears to be a promising method to treat renal cell carcinoma adjacent to renal sinus.
• The estimated 1-, 3- and 5-year RCC-related survival were 100%, 93.3% and 93.3%, respectively.
• The estimated 1-, 3- and 5-year overall survival were 97.1%, 87.8%, 83.6%, respectively.
• For patients with RCC ≤4 cm, initial ablation success was 100% (29/29) and the estimated 5-year disease-free survival were 81.5%.

PurposeTo evaluate the efficacy and safety of ultrasound (US)-guided percutaneous microwave ablation (MWA) for renal cell carcinoma (RCC) adjacent to renal sinus.Materials and methodsThis retrospective study included 41 patients who underwent US-guided percutaneous MWA of 41 RCCs adjacent to the renal sinus from April 2006 to December 2015. Contrast-enhanced images of US and computed tomography (CT) or magnetic resonance (MR) imaging were performed at pre-ablation and 1 day, 1 month, 3 months, and every 6 months after ablation. Initial ablation success (IAS), disease-free survival (DFS), RCC-related survival (RRS), and overall survival (OS) were recorded at the follow-up visits.ResultsIAS was achieved in 92.7% (38/41) of the study subjects. The IAS significantly differed between patients with RCCs ≤4 cm (100%, 29/29) and RCCs >4 cm (75%, 9/12, p = 0.021). During the median follow-up of 37.6 (range, 3.0–97.3) months, the estimated 1-, 3-, and 5-year DFS of patients with an initial tumor of ≤4 cm were 100%, 89.7%, and 81.5%, respectively. The 1-, 3-, and 5-year RRS were 100%, 93.3%, and 93.3%, respectively. The 1-, 3-, and 5-year OS were 97.1%, 87.8%, and 83.6%, respectively. The multivariate analysis using the Cox proportional hazard model revealed no independent predictor of recurrence among all the variables. There were no MWA-related deaths among the study subjects. One patient developed a retroperitoneal abscess after ablation.ConclusionUS-guided percutaneous MWA appears to be a promising method for RCCs adjacent to renal sinus, especially for tumors ≤4 cm.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Radiology - Volume 85, Issue 11, November 2016, Pages 2083–2089
نویسندگان
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