کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4225037 1609748 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The relation between CT findings and sputum microbiology studies in active pulmonary tuberculosis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
پیش نمایش صفحه اول مقاله
The relation between CT findings and sputum microbiology studies in active pulmonary tuberculosis
چکیده انگلیسی


• All micronodules in pulmonary tuberculosis are not of a centrilobular distribution; rather, many are perilymphatic.
• Centrilobular micronodules in pulmonary tuberculosis are associated with positive sputum microbiological results.
• CT features of active lesions in pulmonary tuberculosis are well correlated with sputum studies.

PurposeTo evaluate whether CT findings suggesting active pulmonary tuberculosis correlate with sputum microbiological studies, and to determine whether CT could predict infectivity.Materials and methodsTotal 108 patients with active pulmonary tuberculosis were enrolled. We reviewed CT findings and sputum microbiological studies. Then, we analyzed the statistical difference in CT findings between the positive and negative groups of each sputum microbiological study (AFB smear, PCR, and culture). Also, we divided the patients into five groups according to sputum AFB smear grade and analyzed linear trends of CT findings between the five groups.ResultsBoth frequencies and extents of centrilobular micronodules (63% vs 38%, p = 0.011 for frequency; 1.6 ± 1.6 vs 0.6 ± 1.1, p = 0.001 for extent), tree-in-bud opacities (63% vs 33%, p = 0.002; 1.6 ± 1.6 vs 0.5 ± 0.9, p < 0.001, respectively), consolidation (98% vs 81%, p = 0.003; 2.7 ± 1.5 vs 1.3 ± 1.1, p < 0.001, respectively), and cavitation (86% vs 33%, p < 0.001; 1.5 ± 1.2 vs 0.4 ± 0.7, p < 0.001, respectively), were significantly increased in the sputum AFB-positive group than in the negative group. These four CT findings were increase in frequency and extent in the sputum PCR-positive group with or without statistical significance. They did not show significant differences between the sputum culture-positive and negative groups. As the AFB smear grade increased, frequencies and extents of centrilobular micronodules, tree-in-bud, consolidation, and cavitation also increased.ConclusionCT features representing active tuberculosis—centrilobular nodules, tree-in-bud, consolidation, and, cavitation—strongly correlate with the positivity and grading of AFB smear.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Radiology - Volume 84, Issue 11, November 2015, Pages 2339–2344
نویسندگان
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