کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4225499 | 1609777 | 2013 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Functional MRI using Fourier decomposition of lung signal: Reproducibility of ventilation- and perfusion-weighted imaging in healthy volunteers Functional MRI using Fourier decomposition of lung signal: Reproducibility of ventilation- and perfusion-weighted imaging in healthy volunteers](/preview/png/4225499.png)
PurposeTo assess the reproducibility of Fourier decomposition (FD) based ventilation- and perfusion-weighted lung MRI.MethodsSixteen healthy volunteers were examined on a 1.5 T whole-body MR-scanner with 4–6 sets of coronal slices over the chest volume with a non-contrast enhanced steady-state free precession sequence. The identical protocol was repeated after 24 h. Reconstructed perfusion- and ventilation-weighted images were obtained through non-rigid registration and FD post-processing of images. Analysis of signal in segmented regions of interest was performed for both native and post-processed data. Two blinded chest radiologists rated image quality of perfusion- and ventilation-weighted images using a 3-point scale.ResultsReproducibility of signal between the two time points was very good with intra-class correlation coefficients of 0.98, 0.94 and 0.86 for native, perfusion- and ventilation-weighted images, respectively. Perfusion- and ventilation-weighted images were of overall good quality with proportions of diagnostic images of 87–95% and 69–75%, respectively. Lung signal decreased from posterior to anterior slices with image quality of ventilation-weighted images in anterior areas rated worse than in posterior or perfusion-weighted images. Inter- and intra-observer agreement of image quality was good for perfusion and ventilation.ConclusionsThe study demonstrates high reproducibility of ventilation- and perfusion-weighted FD lung MRI.
Journal: European Journal of Radiology - Volume 82, Issue 6, June 2013, Pages 1015–1022