کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4226176 1609797 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Quantitative assessment of perirectal tumor infiltration with dynamic contrast-enhanced multi-detector row CT in rectal cancer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
پیش نمایش صفحه اول مقاله
Quantitative assessment of perirectal tumor infiltration with dynamic contrast-enhanced multi-detector row CT in rectal cancer
چکیده انگلیسی

ObjectiveTo evaluate the efficacy of discriminant function analysis of perirectal tumor infiltration with dynamic contrast-enhanced 64-detector row CT in rectal cancer.Materials and methodsForty-nine patients with rectal cancer underwent dynamic contrast-enhanced CT. A total of 96 axial CT slices containing the tumors were evaluated. The 96 images were separated into two groups with or without perirectal tumor infiltration based on pathological findings. The discriminant function was set-up using CT density differences between the mass and the adjacent perirectal tissue within 5 mm from the mass at 20 and 40 s as independent variables. The results of the discriminant function analysis were compared to those of CT morphology and pathology.ResultsCT morphological diagnosis was accurate on 71.9% (69/96) of the slices with 82.5% sensitivity and 64.3% specificity. Discriminant function analysis correctly identified 88.5% (85/96) of the slices with 85.0% sensitivity and 91.1% specificity. Overstaging occurred significantly more (P < 0.05) on morphological analysis (20.8%, 20/96) than discriminant function analysis (5.2%, 5/96) of the CT slices.ConclusionsDiscriminant function analysis of dynamic contrast-enhanced CT improves the diagnostic accuracy and specificity of perirectal tumor infiltration in rectal cancer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Radiology - Volume 80, Issue 2, November 2011, Pages 279–283
نویسندگان
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