کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4226374 1609799 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Phantom-less QCT BMD system as screening tool for osteoporosis without additional radiation
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی رادیولوژی و تصویربرداری
پیش نمایش صفحه اول مقاله
Phantom-less QCT BMD system as screening tool for osteoporosis without additional radiation
چکیده انگلیسی

PurposePhantom-less bone mineral density (PLBMD) systems are easily integrated into the CT workflow for non-dedicated Quantitative CT (QCT) BMD measurements in thoracic and abdominal scans. This in vivo retrospective study aims to determine accuracy and precision of the PLBMD option located on the Extended Brilliance Workspace (Philips Medical Systems, Cleveland, OH, US) from both cross-sectional and longitudinal image data.Materials and methodsThe cross-sectional comparison with phantom-based QCT BMD was performed for 82 patients (61 female, 21 male) with a mean age of (63.0 ± 11.8 SD) years on 197 vertebrae. This was followed by an interobserver variability analysis on 71 vertebrae. The longitudinal PLBMD study was carried out on 45 vertebrae from 10 patients (5 female, 5 male) with a mean age of (64.4 ± 11.5 SD) years. They were re-scanned with standardized scan and contrast-injection protocols within a mean and median of (33 ± 41 SD) and 8 days, respectively. All CT scans were acquired on an Mx8000 Quad (Philips) at Florence-Nightingale Hospital, Kaiserswerth, Germany, in a spiral acquisition mode.ResultsA negligible BMD bias of −0.9 mg/cm3 for the PLBMD option was observed with respect to phantom-based QCT BMD. Applying CT number matching of muscle and fat ROIs, the analysis of cross-sectional interobserver and of longitudinal variability yielded precision values of 3.1 mg/cm3 (CV% = 4.0) and 4.2 mg/cm3 (CV% = 5.3), respectively.ConclusionAlthough the precision is inferior to phantom-based BMD systems, PLBMD is a robust clinical utility for the detection of lowered BMD in a large patient population. This can be achieved without additional radiation exposure from non-contrasted CT scans, to perform an ancillary diagnosis of osteopenia or osteoporosis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Radiology - Volume 79, Issue 3, September 2011, Pages 375–381
نویسندگان
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