کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4639523 | 1341238 | 2013 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Computing steady-state solutions for a free boundary problem modeling tumor growth by Stokes equation Computing steady-state solutions for a free boundary problem modeling tumor growth by Stokes equation](/preview/png/4639523.png)
We consider a free boundary problem modeling tumor growth where the model equations include a diffusion equation for the nutrient concentration and the Stokes equation for the proliferation of tumor cells. For any positive radius RR, it is known that there exists a unique radially symmetric stationary solution. The proliferation rate μμ and the cell-to-cell adhesiveness γγ are two parameters for characterizing “aggressiveness” of the tumor. We compute symmetry-breaking bifurcation branches of solutions by studying a polynomial discretization of the system. By tracking the discretized system, we numerically verified a sequence of μ/γμ/γ symmetry breaking bifurcation branches. Furthermore, we study the stability of both radially symmetric and radially asymmetric stationary solutions.
Journal: Journal of Computational and Applied Mathematics - Volume 237, Issue 1, 1 January 2013, Pages 326–334