کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4639523 1341238 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Computing steady-state solutions for a free boundary problem modeling tumor growth by Stokes equation
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات ریاضیات کاربردی
پیش نمایش صفحه اول مقاله
Computing steady-state solutions for a free boundary problem modeling tumor growth by Stokes equation
چکیده انگلیسی

We consider a free boundary problem modeling tumor growth where the model equations include a diffusion equation for the nutrient concentration and the Stokes equation for the proliferation of tumor cells. For any positive radius RR, it is known that there exists a unique radially symmetric stationary solution. The proliferation rate μμ and the cell-to-cell adhesiveness γγ are two parameters for characterizing “aggressiveness” of the tumor. We compute symmetry-breaking bifurcation branches of solutions by studying a polynomial discretization of the system. By tracking the discretized system, we numerically verified a sequence of μ/γμ/γ symmetry breaking bifurcation branches. Furthermore, we study the stability of both radially symmetric and radially asymmetric stationary solutions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Computational and Applied Mathematics - Volume 237, Issue 1, 1 January 2013, Pages 326–334
نویسندگان
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