کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4754877 | 1418376 | 2017 | 32 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The microbiome as engineering tool: Manufacturing and trading between microorganisms
ترجمه فارسی عنوان
میکروبیوم به عنوان ابزار مهندسی: تولید و تجارت بین میکروارگانیسم ها
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کلمات کلیدی
qPCRCHPFTHFSmcrA - MCAAOTU - OTCombined Heat and Power - ترکیب گرما و قدرتchemical oxygen demand - تقاضای اکسیژن شیمیاییMolecular techniques - تکنیک های مولکولیMicrobial community - جامعه میکروبیfluorescent in situ hybridization - فلورسنت در محل hybridizationFish - ماهیoperational taxonomic unit - واحد تاکسونومی عملیاتیpolymerase chain reaction - واکنش زنجیره ای پلیمرازquantitative polymerase chain reaction - واکنش زنجیره ای پلیمراز کمیPCR - واکنش زنجیرهٔ پلیمرازCod - کادو
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی
The integration of microbial technologies within the framework of the water-energy nexus has been taking place for over a century, but these mixed microbial communities are considered hard to deal with 'black boxes'. Process steering is mainly based on avoiding process failure by monitoring conventional parameters, e.g., pH and temperature, which often leads to operation far below the intrinsic potential. Mixed microbial communities do not reflect a randomised individual mix, but an interacting microbiological entity. Advance monitoring to obtain effective engineering of the microbiome is achievable, and even crucial to obtain the desired performance and products. This can be achieved via a top-down or bottom-up approach. The top-down strategy is reflected in the microbial resource management concept that considers the microbial community as a well-structured network. This network can be monitored by means of molecular techniques that will allow the development of accurate and quick decision tools. In contrast, the bottom-up approach makes use of synthetic cultures that can be composed starting from defined axenic cultures, based on the requirements of the process under consideration. The success of both approaches depends on real-time monitoring and control. Of particular importance is the necessity to identify and characterise the key players in the process. These key players not only relate with the establishment of functional conversions, but also with the interaction between partner bacteria. This emphasises the importance of molecular (screening) techniques to obtain structural and functional insights, minimise energy input, and maximise product output by means of integrated microbiome processes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: New Biotechnology - Volume 39, Part B, 25 October 2017, Pages 206-214
Journal: New Biotechnology - Volume 39, Part B, 25 October 2017, Pages 206-214
نویسندگان
Jo De Vrieze, Marlies E.R. Christiaens, Willy Verstraete,