کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4929953 | 1432575 | 2017 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Clozaphobia: Is avoidance of clozapine in diabetes warranted?
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
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چکیده انگلیسی
Despite its superior efficacy, clozapine is an underutilized agent, primarily owing to the “Clozaphobia”-fear of clozapine's adverse effects. Emergent cautions on metabolic side-effects have contributed to avoidance of clozapine prescription. Here, we describe our clinical experience with nine patients having schizophrenia/schizoaffective disorders with comorbid diabetes mellitus and treated with clozapine. Interestingly, all patients could be maintained on optimal glycemic control even after clozapine. In conclusion, a critique on the potential risks versus benefits of clozapine amidst our observations from this case series adds further supporting evidence to the emerging literature on the clinical utility of clozapine in treating schizophrenia patients with diabetes mellitus.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Asian Journal of Psychiatry - Volume 28, August 2017, Pages 142-145
Journal: Asian Journal of Psychiatry - Volume 28, August 2017, Pages 142-145
نویسندگان
Vanteemar S. Sreeraj, Damodaran Dinakaran, Sachin Nagendrappa, Naren P. Rao, Muralidaran Kesavan, Shivarama Varambally, Ganesan Venkatasubramanian,