Synthesis, spectral characterization of novel Pd(II), Pt(II) π-coordination compounds based on N-allylthioureas. Cytotoxic properties and DNA binding ability

Synthesis and characterization of four Pd2 + and Pt2 + π-complexes with N-allylthiourea derivatives have been described. Structures of all compounds were evaluated by single-crystal X-ray diffraction and by H1 and C13 NMR-spectroscopy. All complex compounds possessed pronounced cytotoxic activity “in vitro” and high ability to interaction with DNA.168