Isolation of antioxidant phenolics from Schinopsis brasiliensis based on a preliminary LC-MS profiling

An analytical approach based on LC-ESIMSn was applied to obtain a metabolite profile of the ethanol extract of the stem bark of S. brasiliensis (Anacardiaceae) which guided the isolation of five galloyl derivatives (8, 10-12 and 14) never reported before, along with eleven further phenolic compounds. The antioxidant activity, evaluated by TEAC assay and the cytotoxic activity of all isolated compounds were also investigated.179