The effect of self-aggregation on the determination of the kinetic and thermodynamic constants of the network of chemical reactions in 3-glucoside anthocyanins

► Flavylium cation and quinoidal base of six 3-glucoside anthocyanins self-aggregate. ► Aggregation decreases the hydration constant Kh and increases the acidity constant Ka. ► At low concentration the anthocyanins structure has a small effect on the constants. ► The aggregation efficiency is dependent on the anthocyanins substitution pattern.