کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5418094 | 1506976 | 2007 | 8 صفحه PDF | دانلود رایگان |
Protein database is growing rapidly, but it is difficult to obtain information from protein sequences directly. Therefore, many kinds of methods have been proposed to analyze the protein sequences, the existing methods have their limitations to numerically characterize the protein sequences exactly. Here, we regard a protein sequence as a discrete-time Markov chain and construct transition matrices to numerically characterize it. Based on the properties of Markov chains, we predict the yesterday's, today's, and tomorrow's distributions of every amino acid, from which we can analyze the similarities of different species in the past or in the future. Meanwhile, we give a simple way to evaluate the methods for protein secondary structure prediction.
Journal: Journal of Molecular Structure: THEOCHEM - Volume 803, Issues 1â3, 18 February 2007, Pages 115-122