کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5539022 | 1552815 | 2017 | 27 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Oligodeoxynucleotides CpGs increase silver catfish (Rhamdia quelen) resistance to Aeromonas hydrophila challenge
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم آبزیان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Oligodeoxynucleotides CpGs increase silver catfish (Rhamdia quelen) resistance to Aeromonas hydrophila challenge Oligodeoxynucleotides CpGs increase silver catfish (Rhamdia quelen) resistance to Aeromonas hydrophila challenge](/preview/png/5539022.png)
چکیده انگلیسی
Immune modulation stands up as a strategic management procedures that might overcome the challenges of water-borne pathogens. Synthetic oligodeoxynucleotides (ODNs) containing cytidine-phosphate-guanosine (CpG) motifs are known to activate vertebrate innate immune cells and have been evaluated in several fish species but, to our knowledge, not yet in silver catfish. In this study we analyzed the effect of selected ODN CpGs on their ability to enhance the resistance of silver catfish to a lethal infection with Aeromonas hydrophila. We found that silver catfish pretreated with some ODN CpGs had lower bacterial counts in the blood and the percentile of bacteremic fish was lower compared to control fish. In addition, the survival rate of ODN CpG-treated fish was higher following challenge with A. hydrophila. The effect of ODN CpG 1668, which provided higher protection against challenging bacteria, was dose and time dependent. Our results demonstrate that ODN CpG can induce disease resistance in silver catfish.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Aquaculture - Volume 473, 20 April 2017, Pages 278-282
Journal: Aquaculture - Volume 473, 20 April 2017, Pages 278-282
نویسندگان
RaÃssa Canova, Karina Schreiner Kirsten, Lucas de Figueiredo Soveral, Rafael Frandoloso, Luiz Carlos Kreutz,