کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5545283 1555320 2017 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A cross-sectional study of oral antibacterial treatment patterns in relation to specific diarrhoeal pathogens in weaner pigs
ترجمه فارسی عنوان
یک مطالعه مقطعی از الگوهای درمان ضد باکتری دهان در ارتباط با پاتوژن های خاص اسهال در خوک های خوک
کلمات کلیدی
خوک ها، اسهال، پاتوژن های باکتریایی، انتخاب ضدباکتریایی، تجویز مبتنی بر شواهد،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی
According to international guidelines, the use of antibacterials should be evidence based and prudent. This register-based, cross-sectional study investigates the potential effect of laboratory findings on the patterns of antibacterial oral (batch) medication of weaner pigs, and the level of compliance with national guidelines for antibacterial use. The study population includes 1,736 weaner herds (≈65% of all Danish weaner pigs) that were subject to laboratory analysis from the National Veterinary Institute on Brachyspira pilosicoli, Lawsonia intracellularis, and E.coli (F4 and F18) in 2014. Antibacterial prescription data were obtained from the national database, VetStat. These showed that antibacterial prescriptions for use in weaner pigs was 8.6% lower in spring 2015 compared to spring 2014. The antibacterial use per pig tended (p = 0.08) to decrease more in herds with negative laboratory results compared to herds with a moderate or massive occurrence of either of the pathogens. Irrespective of the laboratory findings on diarrhoeal pathogens, tetracyclines were the most frequently used antibacterials by a substantial margin, both 3 months prior to and 2-5 months after laboratory analysis. According to the national guidelines, tetracyclines are the second or third-choice antibacterial for treatment of diarrhoeal pathogens, due to resistance and co-resistance patterns. Compliance with the guidelines increased in 14% of the herds, mostly following identification of B. pilosicoli within the herd. Between 10% and 20% of the herds did not use batch treatment, despite the presence of moderate-massive amounts of the pathogens.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 203, May 2017, Pages 18-27
نویسندگان
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