The Ventricular Volume Variability Study of the Pediatric Heart Network: Study Design and Impact of Beat Averaging and Variable Type on the Reproducibility of Echocardiographic Measurements in Children with Chronic Dilated Cardiomyopathy

This comprehensive evaluation of quantitative echocardiographic methods will provide a valuable resource for the design of future pediatric studies. BA and a single core lab observer improve the reproducibility of echocardiographic measurements in children with dilated cardiomyopathy. Certain measurements are highly reproducible, while others, despite BA, are poorly reproducible.