Changes in Global Left Ventricular Function by Multidirectional Strain Assessment in Heart Failure Patients Undergoing Cardiac Resynchronization Therapy

Two-dimensional speckle-tracking imaging and AFI enable the quantification of multidirectional LV mechanics. Improvement in LV strain in the 3 orthogonal directions after CRT appears to be a long-term effect and is related to the extent of reverse LV remodeling after CRT.