Clinical and Echocardiographic Variables Fail to Predict Response to Dual-Chamber Pacing for Hypertrophic Cardiomyopathy

Dual-chamber pacing therapy for the relief of symptoms caused by dynamic left ventricular outflow tract obstruction has a limited role because of the availability of more definitive therapies; less than 50% long-term symptom relief; less than 20% long-term relief from a combined end point of death, symptoms, surgery, residual gradient, or a combination of these; and the inability to appropriately identify those patients most likely to derive benefit.