کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5637817 | 1583268 | 2018 | 5 صفحه PDF | دانلود رایگان |
کلید واژه ها
1.مقدمه
2. مواد و روش ها
2-1 اتصال و جداسازی براکت
2-2 جمع آوری مایعات شکافی لثه
2-3 اندازه گیری سیتوکین ها
2-4. پروفایل کمپلکس باکتری
2-5 تحلیل آماری
3. نتایج
4. بحث
5. نتیجه گیری
عناوین جدول ها:
جدول 1: مشخصات آماری جمعیتی و نمرات مشخصه اکلوژن (عدم تناسب ردیف دندان های بالا و پایین )
جدول 2: نمرات مشخصات
رشد قوس بالایی، پوشش پیش آمدگی کمتر دندانهای قدامی، اورجت فوقانی به تحتانی لبه های دندان های قدامی
جدول 3: سطوح سیتوکین سیال شکافی لثه (pg/mL) در سه نوع براکت مختلف
جدول 4: مقایسه بین هر براکت قبل و بعد از 60 روز از اتصال
- The level of TNF-α increased to the SmartClip⢠group without orthodontic movement influence.
- The highest level of the “Red complex” was observed to the SmartClip⢠group.
- The results of TNF-α associated with red complex represent greater inflammatory potential.
- The bracket design should be considered due to the risk of periodontal disease and root resorption.
ObjectiveThe aim of this study was to examine the relationship between bracket design and ratio of five proinflammatory cytokine, in gingival crevicular fluid (GCF), and bacterial adhesion without tooth movement influence.DesignThe sample was comprised of 20 participants, aged 11 to 15 years old (mean age: 13.3 years ± 1.03). A conventional Gemini⢠metallic bracket and two self-ligating brackets, In-Ovation®R and SmartClipâ¢, were bonded to the maxillary incisors and canines. GCF was collected using a standard filter paper strip before and 60 days after bonding. The cytokine levels (IL-12, IL-1α, IL-1β, IL-6 and TNF-α) were performed by the LUMINEX assay. The levels of the red and orange bacterial complexes were analyzed by the Checkerboard DNA-DNA hybridization. The data of cytokine and bacterial complexes were carried out using the non-parametric tests at 5% of significance level.ResultsIncreased cytokine levels were observed. However, only the SmartClip⢠group showed a significantly increased level of TNF-α (p = 0.046). The SmartClip⢠brackets group presented higher levels of red complex bacteria.ConclusionsThe bracket design affected cytokine levels and bacterial adhesion since it was observed that the proinflammatory cytokines released in GCF to the SmartClip⢠group showed an increase in the TNF-α levels associated with higher bacterial levels, which possibly represents greater inflammatory potential. Thereby, the bracket design should be considered in patients with risk of periodontal disease and root resorption.
Journal: Archives of Oral Biology - Volume 85, January 2018, Pages 79-83