Effect of Surgical Modality and Hypofractionated Split-course Radiotherapy on Local Control and Survival from Sinonasal Mucosal Melanoma

En bloc surgery was a prognostic factor on outcomes for local control and survival in this series. Data from the literature have shown that postoperative radiation therapy improves local control. Most series were carried out with conventional fractionation. The effect of planned breaks (split-course radiotherapy) may be deleterious, as suggested in this series. Therefore, split-course radiotherapy cannot be recommended for SHNMM.