کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5766273 1627555 2017 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Overview of the molecular defense systems used by sea urchin embryos to cope with UV radiation
ترجمه فارسی عنوان
بررسی سیستم های دفاعی مولکولی که توسط جنین های یخ زده دریا برای مقابله با اشعه ماوراء بنفش استفاده می شود
موضوعات مرتبط
مهندسی و علوم پایه علوم زمین و سیارات اقیانوس شناسی
چکیده انگلیسی


- We reviewed the defense systems adopted by sea urchin embryos to cope with UVR.
- We describe the UVR response both at the gene and protein levels.
- UVR in combination with other stressors is also summarized.

The sea urchin embryo is a well-recognized developmental biology model and its use in toxicological studies has been widely appreciated. Many studies have focused on the evaluation of the effects of chemical stressors and their mixture in marine ecosystems using sea urchin embryos. These are well equipped with defense genes used to cope with chemical stressors. Recently, ultraviolet radiation (UVR), particularly UVB (280−315 nm), received more attention as a physical stressor. Mainly in the Polar Regions, but also at temperate latitudes, the penetration of UVB into the oceans increases as a consequence of the reduction of the Earth's ozone layer. In general, UVR induces oxidative stress in marine organisms affecting molecular targets such as DNA, proteins, and lipids. Depending on the UVR dose, developing sea urchin embryos show morphological perturbations affecting mainly the skeleton formation and patterning. Nevertheless, embryos are able to protect themselves against excessive UVR, using mechanisms acting at different levels: transcriptional, translational and post-translational. In this review, we recommend the sea urchin embryo as a suitable model for testing physical stressors such as UVR and summarize the mechanisms adopted to deal with UVR. Moreover, we review UV-induced apoptotic events and the combined effects of UVR and other stressors.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Marine Environmental Research - Volume 128, July 2017, Pages 25-35
نویسندگان
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