کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5801823 1112000 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Alphaherpesvirus use and misuse of cellular actin and cholesterol
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Alphaherpesvirus use and misuse of cellular actin and cholesterol
چکیده انگلیسی

Two major structural elements of a cell are the cytoskeleton and the lipid membranes. Actin and cholesterol are key components of the cytoskeleton and membranes, respectively, and are involved in a plethora of different cellular processes. This review summarizes and discusses the interaction of alphaherpesviruses with actin and cholesterol during different stages of the replication cycle: virus entry, replication and assembly in the nucleus, and virus egress. Elucidating these interactions not only yields novel insights into the biology of these important pathogens, but may also shed new light on cell biological aspects of actin and cholesterol, and lead to novel avenues in the design of antiviral strategies.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 143, Issue 1, 16 June 2010, Pages 2-7
نویسندگان
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