کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5815825 1115529 2012 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Unusual increase in lumbar network excitability of the rat spinal cord evoked by the PARP-1 inhibitor PJ-34 through inhibition of glutamate uptake
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Unusual increase in lumbar network excitability of the rat spinal cord evoked by the PARP-1 inhibitor PJ-34 through inhibition of glutamate uptake
چکیده انگلیسی
► Glutamate uptake inhibition by PJ-34 induced persistent synchronous discharges. ► Strong, glutamate-mediated discharges remained even after washout of PJ-34. ► No histological damage was detected 24 h later. ► Fictive locomotion and synaptic reflexes were not impaired. ► Large network excitation was compensated by downsizing synaptic transmission.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuropharmacology - Volume 63, Issue 3, September 2012, Pages 415-426
نویسندگان
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