Influence of skin model on in vitro performance of drug-loaded soluble microneedle arrays

Representative optical coherence tomography images of methylene blue loaded MN dissolving following application to rat skin in vivo. (A) Time = 0 min, (B) time = 3 min, (C) time = 5 min, (D) time = 7 min, (E) time = 10 min, (F) time = 15 min. Scale bar represents a length of 300 μm.