Antioxidant and anti-inflammatory effect of polysaccharides from Lobophora variegata on zymosan-induced arthritis in rats

► Polysaccharides from L. variegata have anti-inflammatory activity in acute induced arthritis in rats. ► Its treatment decrease in cell infiltrate in the synovial membrane with reduction of TNF-α. ► These polysaccharides exhibited power antioxidant activity.