MDG-1, a polysaccharide from Ophiopogon japonicus exerts hypoglycemic effects through the PI3K/Akt pathway in a diabetic KKAy mouse model

MDG-1 was extracted from the tube root of O. japonicus and purified as described previously (Xu et al., 2005). Data from our work suggested that MDG-1, a water-soluble polysaccharide have a marked anti-diabetic effect.199