دانلود مقالات ISI درباره Irs-1 + ترجمه فارسی

تنظیم چرخه ای از گلوکز، چربی و متابولیسم انرژی در انسان

Circadian regulation of glucose, lipid, and energy metabolism in humans

Keywords: CREB; cAMP response element binding protein; AMPK; adenosine monophosphate-activated protein kinase; SCN; suprachiasmatic nucleus; TTFL; transcriptional-translational feedback loop; CR; constant routine; FD; forced desynchrony; CA/M; circadian alignment/m

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

قرار گرفتن در معرض بارداری طولانی مدت در معرض آب آشامیدنی حاوی کروم شش ظرفیتی بیش از حد، سیگنالینگ انسولین را در عضلات کبدی و اسکلتی پروتئین موش دارد

Transient gestational exposure to drinking water containing excess hexavalent chromium modifies insulin signaling in liver and skeletal muscle of rat progeny

Keywords: Chromium toxicity; Glucose homeostasis; Insulin receptor; Glucose transporters; CrVI; Hexavalent chromium; CrIII; Trivalent chromium; IR; Insulin receptor; IRS-1; Insulin receptor substrate-1; GLUT 2/4; Glucose transporters 2/4; ppm; parts per million; GT

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

ادویه جات در مدیریت دیابت

Spices in the management of diabetes mellitus

Keywords: AMPK; 5′ adenosine monophosphate-activated protein kinase; AGE; advanced glycation end-product; BP; blood pressure; CE; cinnamon extracts; CP; cinnamon polyphenols; DM; diabetes mellitus; eNOS; endothelial nitric oxide synthase; FBG; fasting blood gluco

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

اثرات پلئوتروپیک اسید اسکوربیک اسید امگا 3 بر روی علائم بیماری آلزایمر

The pleiotropic effects of omega-3 docosahexaenoic acid on the hallmarks of Alzheimer's disease

Keywords: Aβ; amyloid-β; AβO; Aβ oligomers; βAPP; β-amyloid precursor protein; BDNF; brain-derived neurotrophic factor; CaMKII; calcium/calmodulin-dependent protein kinase II; Cer; cerebellum; ChAT; choline acetyltransferase; Cx; cortex; CxFr; cortex frontal;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی اثربخشی و ریسک درمانهای ضد دیابتی: تجویز داروهای سنتی - تجدیدنظر مکانیکی برای درک نحوه عملکرد آنها

Efficacy and risk profile of anti-diabetic therapies: Conventional vs traditional drugs-A mechanistic revisit to understand their mode of action

Keywords: GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

اثر تیموزین بتا 4 در حضور تنظیم بالای پروتئین سیگنالینگ رشد فاکتور انسولین 1 بر سلولهای اندوتلیال عروقی بالغ گلوکز

Effect of thymosin beta 4 in the presence of up-regulation of the insulin-like growth factor-1 signaling pathway on high-glucose-exposed vascular endothelial cells

Keywords: Tβ4; thymosin beta 4; IGF-1; insulin-like growth factor-1; IGF- 1R; IGF-1 receptor; IRS-1; insulin receptor substrate 1; AKT; phosphotidyl inositol 3-kinase/protein kinase B; GSK3β; glycogen synthase kinase-3 beta; HUVECs; human umbilical vein endotheli

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

رژیم های غذایی غنی از فروکتوز، چربی یا فروکتوز و چربی بدن را تقویت عملکرد مانع روده و منجر به توسعه بیماری های غیر کلامی کبد چرب در طول زمان

Diets rich in fructose, fat or fructose and fat alter intestinal barrier function and lead to the development of nonalcoholic fatty liver disease over time

Keywords: 4-HNE; 4-hydroxynonenal; ALT; alanine-aminotransferase; Arg-1; arginase 1; iNOS; inducible nitric oxide synthase; IR; insulin receptor; IRS-1; insulin receptor substrate 1; MCP-1; monocyte chemotactic protein 1; MyD88; myeloid differentiation primary resp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

مزوتلیوما بدخیم به عنوان یک سرطان ناشی از استرس اکسیداتیو: به روز رسانی

Malignant mesothelioma as an oxidative stress-induced cancer: An update

Keywords: α-TOS; α-tocopheryl succinate; BAP1; BRCA1 associated protein-1; BRCA1; breast cancer susceptibility gene 1; CDK4; cyclin-dependent kinase 4; CEA; carcinoembryonic antigen; CSC(s); cancer stem(-like) cell(s); CTGF; connective tissue growth factor (CCN2)

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

اختلال در گیرنده انسولین 1 سیگنالینگ با مقاومت به انسولین، مانع رشد عصبی و تشدید مرگ سلول های عصبی می شود

Impairment of insulin receptor substrate 1 signaling by insulin resistance inhibits neurite outgrowth and aggravates neuronal cell death

Keywords: BSA; bovine serum albumin; CNS; central nervous system; DCF‐DA; 2′,7′‐dichlorodihydrofluorescein diacetate; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum; HFD; high-fat diet; I/R; insulin resistance; IRS-1; insulin receptor

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

رفع لپه ها به عنوان سیستم عامل اصلی برای تنظیم سیگنالینگ در سرطان

Lipid rafts as major platforms for signaling regulation in cancer

Keywords: Lipid rafts; Signal transduction; IGF-I/PI3K/Akt signaling; Fas/CD95; CASMER; Cancer; APL; alkylphospholipid analogue; CASMER; cluster of apoptotic signaling molecule-enriched rafts; DED; death effector domain; DD; death domain; DISC; death-inducing signa

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

مورفولوژی آدیپوسیت زیر جلدی و آدنومیوم شکم و ارتباط آن با بیان ژن، لیپولیز و آدیپو سیتوکین در زنان

Abdominal subcutaneous and omental adipocyte morphology and its relation to gene expression, lipolysis and adipocytokine levels in women

Keywords: IL-6; Interleukin-6; DXA; dual energy x-ray absorptiometry; BMI; body mass index; HDL; high-density lipoprotein; PPARγ; the nuclear hormone receptor peroxisome proliferator-activated receptor γ; CEBP; CCAAT/enhancer binding protein; PLIN; perilipin; GLU

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

پناهگاه های غشایی به عنوان یک هدف جدید در درمان سرطان

Membrane rafts as a novel target in cancer therapy

Keywords: ADAM; (a disintegrin and metalloprotease) metallopeptidase; ALPs; alkyl-lysophospholipids; CD24; signal transducer CD24 (glycosylphosphatidylinositol-anchored receptor); CD44; CD44 antigen (receptor for hyaluronic acid); CXCR4; chemokine receptor type 4;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

آتروفی عضلانی اسکلتی ناشی از گلوکوکورتیکوئیدی

Glucocorticoid-induced skeletal muscle atrophy

Keywords: FOXO; forkhead box O; GC; glucocorticoids; MuRF-1; muscle RING-finger protein-1; mTOR; mammalian target of rapamycin; IGF-I; Insulin-like Growth Factor-I; eIF4E; eukaryotic translation initiation factor 4E; S6K1; ribosomal protein kinase 1; 4E-BP1; eukary

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

عوامل و مکانیسم های عضله اسکلتی در بیماری مزمن انسدادی ریه

Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease

Keywords: 4E-BP1; 4E-binding protein-1; AA; amino acid; ALS; autophagy-lysosomal system; AMPK; adenosine monophosphate-activated protein kinase; COPD; chronic obstructive pulmonary disease; CRP; C-reactive protein; ERK; extracellular signal regulated kinase; FFM; f

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacological effects and potential therapeutic targets of DT-13

Keywords: ADP; adenosine diphosphate; Akt; protein kinsase B; ALT; alanine transaminase; APD; action potential duration; AST; aspartate transaminase; Atg; autophagocytosis associated protein; CCR5; C, C chemokine receptor type 5; CXCR4; C-X-C chemokine receptor typ

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance

Keywords: aPKC; atypical protein kinase C; ACC; acetyl-CoA carboxylase; ACPD; 2-acetyl-cyclopentane-1,3-dione; AMPK; AMP-activated protein kinase; Akt; protein kinase B; FAS; fatty acid synthase; FoxO1; forkhead homeobox class O1 protein; G6Pase; glucose-6-phosphat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes

Keywords: T2DM; type 2 diabetes mellitus; PTP1B; protein tyrosine phosphatase 1B; BPN; 3,4-dibromo-5-(2-bromo-3, 4-dihydroxy-6-(ethoxymethyl)benzyl) benzene-1,2-diol; GLUT4; glucose transporter 4 translocation; INS; insulin; IR; insulin receptor; IRS-1; IR substrat

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link

Keywords: 3xTg; triple-transgenic; Aβ; β-amyloid; AD; Alzheimer's disease; ADAS-cog; Alzheimer's Disease Assessment Scale-cognitive subscale; Akt; protein kinase B; APP; amyloid precursor protein; CREB; cAMP-response element binding protein; DM; diabetes mell

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

A new hypoglycemic mechanism of catalpol revealed by enhancing MyoD/MyoG-mediated myogenesis

Keywords: CON; control non-treated mice; STZ; streptozotocin; PI3K; phosphatidylinositol‑3‑Kinase; AKT; protein kinase B; GLUT4; glucose transporter protein 4; IRS-1; insulin receptor substrate-1; HG; high glucose; GAPDH; glyceraldehyde 3‑phosphate dehydrogen

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of bisphenol A on metabolism and evidences of a mode of action mediated through endocrine disruption

Keywords: Bisphenol A; BPA; Endocrine disruption; Obesity; Type 2 diabetes; Insulin; BAT; brown adipose tissue; BMI; body mass index; bw; body weight; DES; diethylstilbestrol; DM; Diabete mellitus; ED; endocrine disruptor; eGFR; estimated glomerular filtration; ERR

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Catalpol ameliorates hepatic insulin resistance in type 2 diabetes through acting on AMPK/NOX4/PI3K/AKT pathway

Keywords: HFD; high fat-diet; STZ; streptozotocin; IRS-1; insulin receptor substrate-1; PI3K; phosphatidylinositol 3-kinase; PEPCK; phosphoenolpyruvate carboxykinase; G6pase; glucose 6-phosphatase; FOXO1; forkhead box O1; GSK3β; glycogen synthase kinase-3β; GS; g

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity

Keywords: Vascular smooth muscle; Vasoproliferative disease; Vascular smooth muscle cell; Phenotype switching; Signalling pathways; AJ; adherens junction; ApoE; apolipoprotein E; BMP; bone morphogenetic protein; CAD; coronary artery diseases; CADASIL; cerebral auto

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Atorvastatin impaired glucose metabolism in C2C12 cells partly via inhibiting cholesterol-dependent glucose transporter 4 translocation

Keywords: ABC; ATP-binding cassette; Akt; Protein kinase B; AUC; area under the concentrationtime curve; BW; body weight; CMC; carboxyl methyl cellulose; ERK; extracellular-regulated protein kinase; GCK; glucokinase; GLUT2; glucose transporter 2; GLUT4; glucose tra

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

Keywords: 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5′-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2018 سفارش ترجمه

Data on the expression and insulin-stimulated phosphorylation of IRS-1 by miR-96 in L6-GLUT4myc myocytes

Keywords: MicroRNAs; miR-96; Myocyte; IRS-1; INSR;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Data on the effect of miR-15b on the expression of INSR in murine C2C12 myocytes

Keywords: MicroRNAs; miR-15b; Myocyte; INSR; IRS-1;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Oncogenic mutations of PIK3CA and HRAS in carcinoma of cervix in South Indian women

Keywords: Oncogenic mutations; Cervical cancer; Peripheral blood; PCR-CTPP method; PIK3CA; Phosphatidylinositol-4,5-Bisphosphate; 3-Kinase Catalytic Subunit Alpha; HRAS; Harvey rat sarcoma viral oncogene homolog; EGF; Epidermal Growth Factor; PDGF; Platelet Derived

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Tanshinone I alleviates insulin resistance in type 2 diabetes mellitus rats through IRS-1 pathway

Keywords: Tanshinone I; insulin resistance; type 2 diabetes; IRS-1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways

Keywords: Icariin; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Phosphatidylinositol 3-kinase; Mitogen-activated protein kinase kinase; Dopamine; Parkinson's disease; DA; dopamine; IGF-1R; insulin-like growth factor-1 receptor; IRS-1; insulin receptor substrate-1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

The impact of the IGF-1 system of cancer cells on radiation response - An in vitro study

Keywords: IGF-1R; insulin-like growth factor 1 receptor; SF; surviving fractions; IGF-1R/KR; kinase-deficient IGF-1R; Caco-2-KR4; IGF-1R/KR clone number 4; IRS-1; insulin receptor substrate 1; HRR; homologous recombination repair; NHEJ; non-homologous end joining;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Paeoniflorin ameliorates cognitive dysfunction via regulating SOCS2/IRS-1 pathway in diabetic rats

Keywords: Paeoniflorin; Diabetes; Cognitive dysfunction; SOCS2/IRS-1; Tau phosphorylation; Akt; protein kinase B; DE; diabetic encephalopathy; DM; diabetes mellitus; GSK-3β; glycogen synthase kinase-3β; IL-1β; interleukin-1β; IRS-1; insulin receptor substrate-1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

β-ecdysterone from Cyanotis arachnoidea exerts hypoglycemic effects through activating IRS-1/Akt/GLUT4 and IRS-1/Akt/GLUT2 signal pathways in KK-Ay mice

Keywords: β-EC; β-ecdysterone; ALT; alanine aminotransferase; AMPK; (AMP)-activated protein kinase; DM; diabetes mellitus; FBG; fasting blood glucose; FFA; free fatty acid; GLUT4; insulin-responsive glucose transporter 4; HDL-C; high density lipoprotein cholester

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Flavonoids from Enicostema littorale blume enhances glucose uptake of cells in insulin resistant human liver cancer (HepG2) cell line via IRS-1/PI3K/Akt pathway

Keywords: WHO; World Health Organization; T2DM; Type 2 diabetes mellitus; GLUT; Glucose trasporters; IRS-1; Insulin Substrate Receptor-1; AKT-2; Protein Kinase B; FA; Flavonoid Fraction A; FB; Fraction B; FC; Fraction C; FD; Fraction D; AH; Crude alcoholic extract;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Sn- and Ge- triorganometallics exert different cytotoxicity and modulation of migration in triple-negative breast cancer cell line MDA-MB-231

Keywords: APL; acute promyelocytic leukemia; BSA; bovine serum albumin; DHA; docosahexaenoic acid; DMSO; dimethylsulfoxide; ER; estrogen receptor; FDA; fluorescein diacetate; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; HER-2; human epidermal growth fac

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis

Keywords: CYP2A6; Cytochrome P450 2A6; CYP2E1; Cytochrome P450 2E1; Cyp2e1−/− mice; Cyp2e1 knockout mice; CYP2A5; Cytochrome P450 2A5; Cyp2a5−/− mice; Cyp2a5 knockout mice; NRF2; nuclear factor-erythroid 2-related factor 2; Nrf2−/− mice; Nrf2 knockout m

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells

Keywords: AG; aminoguanidine; AGE; advanced glycation end-product; Akt; protein kinase B; eNOS; endothelial NO synthase; ERK; extracellular signal-regulated protein kinase; Glo1; glyoxalase 1; HDAC; histone deacetylase; HUVECs; human umbilical vein endothelial cell

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Small heterodimer partner (SHP) contributes to insulin resistance in cardiomyocytes

Keywords: Acaca; acetyl-CoA carboxylase; Acadvl; acyl-CoA dehydrogenase, very long chain; Acot1; acyl-CoA thioesterase 1; Acox1; acyl-CoA oxidase 1; AS160; AKT substrate of 160 kDa; BSA; bovine serum albumin; Cpt1b; carnitine palmitoyltransferase I; DBD; DNA bindi

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells

Keywords: microRNA; miR-1271; Saturated fatty acid; Palmitate; Insulin resistance; INSR; IRS-1; Akt2; v-akt murine thymoma viral oncogene homolog 2; C/EBPα; CCAAT/enhancer binding protein alpha; ER; endoplasmic reticulum; FOXQ1; forkhead box Q1; GPC3; glypican 3;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

The roles of extracellular related-kinases 1 and 2 signaling in CNS myelination

Keywords: Erk; Akt; Fyn; BDNF; Oligodendrocyte; Myelin; Erk1/2; extracellular related-kinase 1 and 2; BDNF; brain-derived neurotrophic factor; NGF; nerve growth factor; NT-3; neurotrophin 3; CNS; central nervous system; PNS; peripheral nervous system; p75NTR; p75 n

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Elucidation of hypoglycemic action and toxicity studies of insulin-like protein from Costus igneus

Keywords: BCA; bicinchoninic acid; ILP; insulin-like protein from Costus igneus; DMEM; Dulbecco's Modified Eagle's Medium; FBS; fetal bovine serum; GLUT-4; glucose transporter-4; IR; insulin receptor; IRS-1; insulin receptor substrate-1; 2-NBDG; [2-{N-(7-nitrob

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

N − 3PUFA differentially modulate palmitate-induced lipotoxicity through alterations of its metabolism in C2C12 muscle cells

Keywords: 2-NBDG; fluorescent glucose analog; ALA; alpha-linolenic acid; AMPK; AMP-activated protein kinase; AS160; AKT substrate of 160 kDa; cpt1; carnitine palmitoyltransferase 1; DMEM; Dulbecco's modified eagle medium; DHA; docosahexaenoic acid; DPH; diphenyl-h

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Mitochondrial-generated ROS down regulates insulin signaling via activation of the p38MAPK stress response pathway

Keywords: p38MAPK; IRS-1; AKT/PKB; GSK3β; Serine phosphorylation; Mitochondrial dysfunction

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Oral administration of SR-110, a peroxynitrite decomposing catalyst, enhances glucose homeostasis, insulin signaling, and islet architecture in B6D2F1 mice fed a high fat diet

Keywords: Diabetes; Peroxynitrite; Glucose homeostasis; Islet architecture; Insulin content; Nitrotyrosine; Insulin signaling; HFD; high fat diet; IPGTT; intra-peritoneal glucose tolerance test; mAB; monoclonal antibody; SR-135; Mn(III) complex of 3,5-bis(hydroxyph

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Antisense molecules: A new class of drugs

Keywords: Clinical trial; antisense; small interfering RNA; DNAzyme; therapy; ALS; Amylotrophic lateral sclerosis; AMD; Age-related macular degeneration; CMV; Cytomegalovirus; CNV; Choroidal neovascularization; CVD; Cardiovascular disease; DMD; Duchenne muscular dy

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Intrathecal administration of rapamycin inhibits the phosphorylation of DRG Nav1.8 and attenuates STZ-induced painful diabetic neuropathy in rats

Keywords: STZ; streptozotocin; PDN; painful diabetic neuropathy; DRG; dorsal root ganglion; mTOR; mammalian target of rapamycin; S6K; ribosomal protein S6 kinase; 4E-BP; eukaryotic initiation factor 4E (eIF4E) binding protein; IR; insulin receptor; IRS-1; insulin r

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Entada phaseoloides extract suppresses hepatic gluconeogenesis via activation of the AMPK signaling pathway

Keywords: ACC; acetyl coenzyme A carboxylase; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AMPK; AMP-activated protein kinase; CCK-8; cell counting kit-8; Dex/cAMP; dexamethasone/cAMP; Entada phaseoloides; Entada phaseoloides (L.) Merr.; G6pase; glu

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2016 سفارش ترجمه

The downward spiral of periodontitis and diabetes in Alzheimer׳s disease: Extending healthy life expectancy through oral health

Keywords: AD; Alzheimer׳s disease; Dian; Dominantly Inherited Alzheimer Network; Aβ; amyloid β peptides; IRS-1; insulin receptor substrate 1; qRT-PCR; quantitative real-time reverse-transcription polymerase chain reaction; TNF-α; tumor necrosis factor-α; ROS;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

N-myristoylated ubiquitin ligase Cbl-b inhibitor prevents on glucocorticoid-induced atrophy in mouse skeletal muscle

Keywords: Cbl-b; IRS-1; Mice; Skeletal muscle atrophy; Ubiquitin ligase inhibitor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

A review on the possible molecular mechanism of action of N-acetylcysteine against insulin resistance and type-2 diabetes development

Keywords: N-acetyl-l-cysteine (NAC) (PubChem CID: 12035); AKT; protein kinase B; AP-1; activator protein 1; CCL2; chemokine (C-C motif) ligand 2; eNOS; endothelial nitric oxide synthase; ERK; extracellular signal-regulated kinase; FFA; free fatty acid; GLUT; gluc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-7: A miRNA with expanding roles in development and disease

Keywords: ACK1; activated CDC42 kinase 1; BASP1; brain abundant, membrane attached signal protein 1; c-Myc; v-Myc avian myelocytomatosis viral oncogene homolog; CD57; cluster of differentiation 57; CD44; cluster of differentiation 44; ciRS-7; circular RNA sponge fo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه