Radiosensitization to X-ray radiation by telomerase inhibitor MST-312 in human hepatoma HepG2 cells

These data demonstrated that disturbances of telomerase function could enhance the radiosensitivity of HepG2 cells to X-ray irradiation by impairing HR repair processes. In addition, telomerase inhibitor MST-312 may be useful as an adjuvant treatment in combination with irradiation.