کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5856629 | 1131979 | 2015 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Navigating through orphan medicinal product regulations in EU and US - Similarities and differences
ترجمه فارسی عنوان
هدایت از طریق مقررات داروهای دارویی در اتحادیه اروپا و ایالات متحده - شباهت ها و تفاوت ها
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کلمات کلیدی
CFREMANIHMHLWCOMPCHMPFDAMinistry of Health, Labour and WelfareEuropean Medicines agency - آژانس دارویی اروپاEuropean Union - اتحادیه اروپاFood and Drug Administration - سازمان غذا و داروNational Institute of Health - موسسه ملی بهداشتCode of Federal Regulations - کد قوانین فدرالCommittee for Medicinal Products for Human Use - کمیته دارویی برای استفاده انسانیEuropean Commission - کمیسیون اروپایی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
Rare diseases as the name suggests are the diseases which occur in a very small population due to which the development of medicinal products for these diseases is sidelined as it is anticipated that the cost of development will never be recovered from the sales. It has been estimated by National Institute of Health (NIH) that globally around 7000 rare diseases are there, many of which are of genetic origin. This paper aims to analyze the basic similarities and differences between the rules and regulations put forth by regulatory agencies of US and EU for development of medicinal products for rare diseases, also called orphan medicinal products. The basic purpose was to carve out the loopholes as well as positive aspects of each of these acts and regulations so as to have a clear understanding on the subject. It was to understand that how these legal instruments have stimulated the growth of the drug products for rare diseases and what other things can be done in order to achieve a better impact. This article also provides an overview of the various incentives offered as well as challenges and hurdles faced by each of these regulatory agencies while implementing these regulations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regulatory Toxicology and Pharmacology - Volume 71, Issue 1, February 2015, Pages 63-67
Journal: Regulatory Toxicology and Pharmacology - Volume 71, Issue 1, February 2015, Pages 63-67
نویسندگان
Jyoti Tiwari,