کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5858567 | 1562177 | 2013 | 34 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Markers of oxidative stress in follicular fluid of women with endometriosis and tubal infertility undergoing IVF
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Markers of oxidative stress in follicular fluid of women with endometriosis and tubal infertility undergoing IVF Markers of oxidative stress in follicular fluid of women with endometriosis and tubal infertility undergoing IVF](/preview/png/5858567.png)
چکیده انگلیسی
Oxidative stress and trace elements in the oocytes environment is explored in endometriosis and impact on in vitro fertilization (IVF) outcome assessed. Follicular fluid was aspirated at the time of oocyte retrieval from endometriosis (n = 200) and tubal infertility (n = 140) and the analytes measured using spectroscopy and HPLC. Increased concentration of reactive oxygen species (ROS), nitric oxide (NO), lipid peroxidation (LPO), iron, lead, cadmium and reduced levels of total antioxidant capacity (TAC), superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx), glutathione reductase (GR), vitamins A, C, E, copper, zinc and selenium was observed compared to tubal infertility. Increased ROS and NO in endometriosis and tubal infertility associated with poor oocytes and embryo quality. Increased levels of ROS, NO, LPO, cadmium and lead were observed in women who did not become pregnant compared to women who did. Intrafollicular zinc levels were higher in women with endometriosis who subsequently became pregnant following IVF.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive Toxicology - Volume 42, December 2013, Pages 116-124
Journal: Reproductive Toxicology - Volume 42, December 2013, Pages 116-124
نویسندگان
Abhay K. Singh, Ratna Chattopadhyay, Baidyanath Chakravarty, Koel Chaudhury,