کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5858606 | 1562177 | 2013 | 7 صفحه PDF | دانلود رایگان |
- We examined developmental exposure effect of electromagnetic field on rat testicle.
- Prenatal exposure to electromagnetic field adversely affects rat testicle development.
- Lipid peroxidation levels increases prenatal electromagnetic field exposed rats.
- Apoptotic index increases in testicles prenatal electromagnetic field exposed rats.
- DNA oxidation increases in rats exposed to electromagnetic field in the prenatal term.
The aim of this study was to investigate the effect of exposure to a 900-MHz electromagnetic field (EMF) in the prenatal term on the 21-old-day rat testicle. Pregnant rats were divided into control (CG) and EMF (EMFG) groups. EMFG was exposed to 900-MHz EMF during days 13-21 of pregnancy. Newborn CG rats were obtained from the CG and newborn EMFG (NEMFG) rats from the EMFG. Testicles were extracted at postnatal day 21. Lipid peroxidation and DNA oxidation levels, apoptotic index and histopathological damage scores were compared. NEMFG rats exhibited irregularities in seminiferous tubule basal membrane and epithelium, immature germ cells in the lumen, and a decreased diameter in seminiferous tubules and thickness of epithelium. Apoptotic index, lipid peroxidation and DNA oxidation were higher in NEMFG rats than in NCG. 21-day-old rat testicles exposed to 900-MHz EMF in the prenatal term may be adversely affected, and this effect persists after birth.
Journal: Reproductive Toxicology - Volume 42, December 2013, Pages 203-209