Investigation of the cumulative body burden of estrogen-3,4-quinone in breast cancer patients and controls using albumin adducts as biomarkers

► We compared the body burden of estrogen quinones in Taiwanese women with breast cancer and controls. ► Serum E2-3,4-Q was inversely proportional to BMI among premenopausal women. ► Elevation of body burden of E2-3,4-Q may play a role in the development of breast cancer.