Analysis of gene expression changes to elucidate the mechanism of chilling injury in precision-cut liver slices

► Precision-cut liver slices as a model to study the mechanism of chilling injury. ► The mechanism of chilling injury on PCLS was studied by microarray array analysis. ► The mechanism of chilling injury was studied in PLCS without other damaging events. ► Chilling affects stress and immune response and lipid/cholesterol metabolism.